Occupational therapists (OTs) are health care professionals specializing in occupational therapy and occupational science. OTs and occupational therapy assistants (OTAs) use scientific bases and a holistic perspective to promote a person's ability to fulfill their daily routines and roles. OTs have immense training in the physical, psychological, and social aspects of human functioning deriving from an education grounded in anatomical and physiological concepts, and psychological perspectives. They enable individuals across the lifespan by optimizing their abilities to perform activities that are meaningful to them ("occupations"). Human occupations include activities of daily living, work/vocation, play, education, leisure, rest and sleep, and social participation.

OTs work in a variety of fields, including pediatrics, orthopedics, neurology, low vision therapy, physical rehabilitation, mental health, assistive technology, oncological rehabilitation, and geriatrics. OTs are employed in healthcare settings such as hospitals, nursing homes, residential care facilities, home health agencies, outpatient rehabilitation centers, etc. OTs are also employed by school systems, and as consultants by businesses to address employee work-related safety and productivity. Many OTs are also self-employed and own independent practices. In the United States, OTs are also employed as commissioned officers in the Army, Navy and Air force branches of the military. In the US Army, OTs are part of the Army Medical Specialist Corps. OTs are also a part of the United States Public Health Service Commissioned Corps, one of eight uniformed services of the United States.

Occupational therapy interventions are aimed to restore/ improve functional abilities, and/or alleviate/ eliminate limitations or disabilities through compensatory/adaptive methods. OTs, thus, evaluate and address both the individual's capacities and his/ her environment (physical and psycho-social) in order to help the individual optimize their function and fulfill their occupational roles. They often recommend adaptive equipment/ assistive technology products and provide training in its use to help mitigate limitations and enhance safety.